So I have a work-up by an endocrinologist. She calls to tell me I have no estrogen whatsoever. What the bleep? Since the ovaries are just fine, she wants me to get a head scan of the pituitary/hypothalamus axis. And also a lung x-ray to rule out sarcoidosis. My rheumy finds this to be fascinating, and feels that this may be a significant clue as to what's causing all my pain. Pain is really my ONLY symptom, that and loss of menses for 6 months or so. Anyone else have absolutly NO estrogen? If so, did you ever find out the cause? Thanks in advance for any and all replies!