Hi Lucky, I know you posted your question to Amelia, but just wanted to respond too. I`m delighted the OLE is working for you, and yes we noticed irritability too. My daughter had Mycoplasma Pneumoniae, her energy levels improved a lot within 6 wks on OLE. As to how long you take it for is another question. Mycoplasma can take a loooong time to eradicate, Dawn has been on and off OLE since last October. Length of time depends on what you are treating. In my literature it says to have OLE as though it were the usual Antibiotic, so use it basically to do a job, not just as an every day preventative. Can I suggest you take it for about 2 months, take a break, and resume again perhaps week day only. You need to have the breaks though I expect you will find a routine that best suits you anyway. We found after a while that we would forget to take the OLE some days, which I guess means we must have been feeling better. But on the whole, the OLE only comes out now when any of us pick up a virus. My favourite product for this and which I highly recommend for you is one by Higher Nature, it has Echinacea,& Black Elderberry on the front label, and listed on the back is OLE & Myrrh. £6.90 here so about $10. This stuff is DYNAMITE on throat/ear/chest infections - my stepson was CURED within 3 days of bronchitis on this product. Dawn had a very flemmy chest too at the same time - GONE within 3 days also. You`ve got to try this one. Hope this helps you, Love Pat.