I brought an article in to my doctor about how provigil has helped people with CFS and FMS. After reading it he agreed to give it a try. Again i started out feeling a little anxious and agitated but got passed it. Not everyone can though. My doctor has been very good at doing anything i ask of him....he realizes i know more about CFS and FMS and as long as i show him articles and plenty of them he has been great about it.Good luck.