My Rhuemy recently put me on a low dosage of Plaquenil (200mg, 2x day) in addition to the 400mg Lodine and 650mg Acetaminophen. i'm wondering what your experiences with Plaquenil have been. So far, second day I seem to have no side effects. Maybe a little cramping, but my period's also due, so I'm not sure about that. Also, how long did it take you to feel any effects? And,did it really stop the inflammation to the point where you didn't need this drug anymore? Thanks.