I was thinking about all the potential things that could have contributed to me getting cfs and one thing that happened a year before I really lost it was going swimming in park lake in wisconsin and seeming to get some itch/dermatitis on face after that and it recurred, but no dermatologist acknowledget the swimming could be related and just called it rosacea. Anyway a lot of other things went wrong the next year that contributed to my downfall but I wonder if this ties in as well and if it would be worth it to take the praziquantel at this point, 20 years later. artesunate is being used for it too. the interesting things is that it hasnt been acknowledged that Human schistosomiasis happened in midwest in the 80s, they would probly say other causes for swimmers itch. but my research the other day seemed to indicate that worst case scenario left unchecked Human schistosomiasis could cause gut problems and spinal pain problems etc. It doesnt seem tradl med though is looking at this as a common possibility in fm and cfs right now. Human schistosomiasis Original Text Prof Bruno Gryseels MD a Corresponding AuthorEmail Address, Katja Polman PhD a, Jan Clerinx MD a, Prof Luc Kestens PhD a Summary Schistosomiasis or bilharzia is a tropical disease caused by worms of the genus Schistosoma. The transmission cycle requires contamination of surface water by excreta, specific freshwater snails as intermediate hosts, and human water contact. The main disease-causing species are S haematobium, S mansoni, and S japonicum. According to WHO, 200 million people are infected worldwide, leading to the loss of 1·53 million disability-adjusted life years, although these figures need revision. Schistosomiasis is characterised by focal epidemiology and overdispersed population distribution, with higher infection rates in children than in adults. Complex immune mechanisms lead to the slow acquisition of immune resistance, though innate factors also play a part. Acute schistosomiasis, a feverish syndrome, is mostly seen in travellers after primary infection. Chronic schistosomal disease affects mainly individuals with long-standing infections in poor rural areas. Immunopathological reactions against schistosome eggs trapped in the tissues lead to inflammatory and obstructive disease in the urinary system (S haematobium) or intestinal disease, hepatosplenic inflammation, and liver fibrosis (S mansoni, S japonicum). The diagnostic standard is microscopic demonstration of eggs in the excreta. Praziquantel is the drug treatment of choice. Vaccines are not yet available. Great advances have been made in the control of the disease through population-based chemotherapy but these required political commitment and strong health systems.