Hi, I haven't posted for quite awhile. Hello again! For the record, I have fibro, was diagnosed about 10 years ago. I manage it pretty well most of the time, but there's always room for improvement. Lately there's been lots of room to improve. My doctor gave me samples of a new medication today, called Pristiq. It regulates serotonin and norepinephrine, is supposed to help with pain and depression. I'm more concerned about pain lately, but help with both wouldn't hurt. I was on Cymbalta for about 2 months, stopped it in mid-May, and will NEVER take it again. Ever. My concern is whether Pristiq has similar side effects as Cymbalta? Has anyone here taken it? I'd very much like to hear about your experiences, as I am trying to decide if I should try yet another medication. My experience with Cymbalta was so unpleasant, I am a little 'gun-shy' now. Peace, Beth.