Well my new doc recommended I try Fluoxetine (Prozac) to see if it would help my CFS, but I have now stopped it after taking only 2 pills as it seems to adversely affect my sleep. I generally can't get to sleep before about 530am at the moment and ususally awake around 1 or 2pm but with the Prozac I woke around 1030am so only slept around 4/5 hrs. It seemed to stop me sleeping through a layer of fatigue in my head and left me feeling weak and fragile. Maybe I should have tried it for longer but I could not continue to take something that was making me feel worse. Perhaps I need to sort out my sleep cycle before I try it again? Any advice or experiences appreciated.