I was wondering if anyone on xyrem could tell me how long it took them to get to the right dosage. I have been on the lowest dost for two weeks and my dr. says that I need to stay on that amount for a month and then he may adjust the dose. I have not experienced any significant improvements on this low dose and was wondering what others might have experienced. My main problem is fatigue/cognitive difficulties. My sleep study results reflect no stage 3 or 4.