Thank you so much for all of your responses to my posts. You said that some of the meds that I take may interact with Klonopin. Do you know which ones and why. I have just started Vioxx and since it's not working yet I take Ultracet as needed. I find it does very little, but does make a small dent. I take wellbutrin for depression. I did not do well on SSRIs such as paxil and zoloft. Without an antidepressant I would have no life. I also take zanaflex, which was prescibed to help me sleep. It helps me go to sleep, but wears off quickly. It does give me a little relief during the day when even holding me head up hurts, but I have to take a small dose. Now that I have gone completely off the subject, which meds would you consider cutting out and why?