So i was reading the post about Dr Myhill and got the part about trying to shift cells away from glycolysis and towards aerobic respiration. the substance mentioned that could do that was dichloroacetate (DCA). it works by inhibiting pyruvate dehydrogenase kinase which in turn upregulates pyruvate dehydrogenase. This "decreases lactate production by shifting the metabolism of pyruvate from glycolysis towards oxidation in the mitochondria.." from Wikipedia... anyway reading made me wonder if there were other substances that inhibit this same enzyme. did a little Googling and found this: R-lipoic acid inhibits mammalian pyruvate dehydrogenase kinase http://cat.inist.fr/?aModele=afficheN&cpsidt=16213010 apparently this form of Lipoic Acid could potentially do something similar to dichloroacetate. and it makes me wonder if you combined one of these protocols aimed addressing cellular energy production with R Lipoic acid if it would better help the shift away from glycolysis. interestingly, there is some research about R Lipoic Acid in Alzheimer's and Cardiovascular disease..