Reglan licensed for GERD

Discussion in 'Fibromyalgia Main Forum' started by ulala, Mar 14, 2009.

  1. ulala

    ulala New Member

    I had an IVIG this past week and had IV Reglan because of some nausea. It made me feel and sleep much better. I just did a search on it to see how I could get more and found that it'is approved for GERD. A similar drug, Zofran (for nausea) has also made me feel better and may help with ERD.

    Reglan® (metoclopramide) is licensed for the short-term treatment of diabetic gastroparesis and gastroesophageal reflux disease (GERD). It is available by prescription only and comes in several different forms, including tablets, an oral solution, and an injection. The medication works for diabetic gastroparesis by helping food move through the stomach more quickly and helps improve GERD symptoms by preventing the stomach contents from refluxing back up the esophagus. Impotence, fatigue, and breast leakage are some of the potential side effects of Reglan.

  2. ulala

    ulala New Member

    about stomach acid relief...

    Helicobactor pylori infestation, a common bacterial cause of gastritis and ulcers, is typically treated with a combination of drugs. The typical combination includes antibiotics, a bismuth compound, and a proton pump inhibitor. (Proton pump inhibitors reduce stomach acid secretion.) These drugs are usually taken for at least 14 days.

    In addition to the medications used for Helicobacter pylori infection, other medications that may be used to relieve symptoms of gastritis include those that reduce stomach acid secretion:

    * Antacids such as calcium carbonate and magnesium hydroxide with aluminum salts
    * H2 blockers such as ranitidine, cimetidine, nizatidine, and famotidine
    * Proton pump inhibitors such as omeprazole and lansoprazole

    Drugs that reduce stomach acid secretion help protect against or treat ulcers. Other drugs used for ulcers include:

    * Misoprostol – protects against the major intestinal toxicity of NSAIDS, and can reduce the formation of ulcers
    * Sucralfate – helps to heal ulcers in the stomach

    Nutrition and Dietary Supplements

    Eating a diet high in fiber may not only cut your risk of developing ulcers in half, but fiber-rich foods may also speed the healing of ulcers. Fruits and vegetables are particularly protective sources of fiber and seem to reduce the amount of inflammation in the lining of the stomach; fruit juice appears to have this benefit as well. Plus, if you didn't have enough reasons to avoid fat in your diet already, animal studies suggest that high fat foods may lead to gastritis.

    Consumption of foods and beverages that irritate the lining of the stomach or increase the stomach acids should be avoided completely or reduced, and known allergens eliminated. These often include:

    * Alcohol
    * Acidic drinks such as coffee (with and without caffeine)
    * Milk
    * Carbonated beverages
    * Spices and peppers (for some people this is important, while for others such foods do not seem to cause symptoms or inflammation)

    Gamma-linolenic acid (GLA)

    Very preliminary evidence from test tube and animal studies suggest that gamma-linolenic acid (GLA) from evening primrose oil (EPO) may have anti-ulcer properties. GLA is an essential fatty acid (EFA) in the omega-6 family that is found primarily in plant-based oils, including EPO and borage seed oil. Although studies are promising, it is too early to know how this might apply to people with gastritis.


    Healthy or "friendly" organisms, called probiotics, inhabit the lining of the intestines and protect us from the entrance of "bad" infections that can cause disease. Lactobacillus acidophilus (L. acidophilus) is the most commonly used probiotic. In test tube studies, L. acidophilus and other probiotics were able to kill or slow down the growth of H. pylori; research is needed to understand whether that benefit would occur in people. One way in which probiotics may help is by reducing side effects, such as diarrhea and taste disturbance, from medications used to treat H. pylori.

    Vitamin B12

    People with pernicious anemia and H. pylori infection are deficient in vitamin B12. Supplementation with this vitamin may be used to treat both. Good dietary sources of vitamin B12 include fish, dairy products, organ meats (particularly liver and kidney), eggs, beef, and pork.


    The following appear promising, but more research is needed before these nutrients become a part of treatment for gastritis, its symptoms, or its complications:

    * Bromelain (Ananas comosus) -- the protein-digesting enzymes found in bromelain (derived from pineapple) help promote and maintain proper digestion and may relieve symptoms of stomach upset or heartburn, particularly when used with other enzymes such as amylase (which digests starch) and lipase (which digests fat). Studies in people are needed.
    * Vitamin A – found in many fruits and vegetables, is thought to increase the benefit of these foods (which are also rich in fiber as discussed earlier). One study suggests that the combination of vitamin A and antacids may be more effective than antacids alone in healing ulcers.
    * Vitamin C -- in one study, high-dose vitamin C treatment for four weeks effectively treated H. pylori infection in some, but not all, people. In addition, H. pylori appears to impair absorption of vitamin C, which may play a role in the higher risk of stomach cancer for those with this organism in their gastrointestinal tract.


    Herbs may cause side effects or interact with medications. They should, therefore, be used with caution and only under the guidance of a professionally trained and qualified herbalist. With that said, there are many herbs, some of which are described below, that may be recommended by an herbal specialist for symptoms of gastritis. The herbalist would work with you to individualize your treatment.

    * Astragalus (Astragalus membranaceus) – used traditionally to treat stomach ulcers. May also prevent the damage from radiation or chemotherapy that can lead to gastritis.
    * Barberry (Berberis vulgaris)- This herb contains active substances called berberine alkaloids. These substances have been shown to combat infection and bacteria. For this reason, barberry is used to ease inflammation and infection of the gastrointestinal tract. Barberry has also been used traditionally to improve appetite.
    * Bilberry (Vaccinium myrtillus) - Studies in rats have found that anthocyanidins (an antioxidant) from bilberry fruits help prevent stomach ulcers caused by a variety of factors including stress, medications, and alcohol. Whether this will translate into help for people requires research.
    * Cat's Claw (Uncaria tomentosa) – The bark and root of this herb have been used among indigenous people of the rainforest for centuries to treat a variety of health problems including ulcers and other gastrointestinal disorders. The benefits of this herb may be due to its ability to reduce inflammation.
    * Chamomile, Roman (Chamaemelum nobile) - Traditionally, Roman chamomile has been used to treat nausea, vomiting, heartburn, and excess intestinal gas.
    * Cranberry (Vaccinium spp.) – may have properties that help prevent H. pylori.
    * Dandelion (Taraxacum officinale) - Native Americans have traditionally used dandelion to treat kidney disease, heartburn and stomach upset, amongst other conditions. Chinese medicinal practitioners traditionally used dandelion to treat digestive disorders, Today, dandelion roots are primarily used as an appetite stimulant and digestive aid. If you have gallbladder disease, you should not use dandelion.
    * Devil's Claw (Harpagophytum procumbens) - many professional herbalists consider devil's claw to be useful for upset stomach and loss of appetite.
    * Dong Quai (Angelica sinensis) - animal studies suggest that dong quai may soothe ulcers, but studies in people are needed before a definitive conclusion can be drawn.
    * Ginger (Zingiber officinale) – In China, ginger has been used to aid digestion and treat stomach upset as well as nausea for more than 2,000 years. This herb is also thought to reduce inflammation.
    * Green Tea (Camellia sinensis) – Population based studies conducted in Japan suggests that people who drink green tea regularly may be protecting themselves from developing chronic gastritis.
    * Licorice (Glycyrrhiza glabra) - this herb is a demulcent (soothing, coating agent) that has long been valued for its use in food and medicinal remedies, including treatments for stomach ailments. Some licorice root extracts, known as deglycyrrhizinated licorice (DGL), still have the healing properties of licorice without the harmful effects (like high blood pressure). DGL may be better for stomach or duodenal ulcers and may even be as effective as some prescription drugs for stomach ulcers.
    * Slippery elm (Ulmus fulva) - Although there has been little scientific research on slippery elm, it has a long history of use based on clinical experience. Gastritis and peptic ulcer are among the conditions that seem to respond to slippery elm.
    * Turmeric (Curcuma longa) -Turmeric has long been used in both Ayurvedic and Chinese medicine to treat digestive disorders. Scientific research is beginning to test the merit of this traditional use. In an animal study, for example, extracts of turmeric root reduced the release of acid from the stomach and protected against injuries such as gastritis or inflammation of the intestinal walls and ulcers. Further studies are needed to know to what extent these protective effects apply to people as well. (Note: at very high doses, turmeric may induce ulcers. It is very important to stick with the dose recommended by an herbal specialist.)
    * Yarrow (Achillea millefolium) – Used traditionally to reduce inflammation, increase appetite, and ease stomach upset.


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