Results of study: New antidepressants vs. old antidepressants

Discussion in 'Fibromyalgia Main Forum' started by abbylee, Sep 24, 2005.

  1. abbylee

    abbylee New Member

    Apparently a study was done in which the new, more expensive antidepressants were found to be no better than the older, cheaper ones in helping patients with depression.

    If you are having problems paying for your meds, you may want to investigate changing to an older antidepressant.

    It's a shame that we've not made more progress in developing antidepressants.

  2. stillfighting

    stillfighting New Member


    I'm not surprised that on average, the new antidepressants are no better than the old ones. But for some folks, the old ones didn't work well or caused unacceptable side effects, and the new ones work for them. It is important to examine the scientific studies on which these conclusions are based.

    But, that said, if a medication is working well for you and the side effects are not a problem, it doesn't make sense to switch to a new med just because it is newer. My rheumy has a "newer is better" attitude about Klonopin v. Neurontin or even the son of Neurontin (I forget the name). I was having problems with occasional neuropathy in my hands and feet that wasn't being controlled by any of the meds I was taking, so he wanted to get me off Klonopin and switch me to Neurontin. I couldn't sleep, the neuropathy got worse, and the cramps started up again. I'm back on Klonopin--well at least he recognized that newer is not necessarily better (at least in my case) :)!

  3. Mikie

    Mikie Moderator

    Several of my docs tried me on Celebrex, Vioxx, and Ultram. All of them made me sick--thank God or I might have suffered the side effects of the Vioxx.

    My pain specialist put me on Morphine and it worked great. It's cheap, effective, and it's been around for a long time, long enough so that we know the side effects.

    As long as the pill companies can convince the docs that their newest, greatest version of meds is better, docs will continue to prescribe the newer, more expensive drugs.

    This is one of the reasons we have such problems with ABX. Instead of using ones which have worked in the past, the docs keep prescribing the new ones which should be reserved for when the older ones don't work. Profits climb while the pathogens mutate, necessitating even newer and more expensive ABX. It's a hideous and dangerous cycle.

    Love, Mikie
  4. abbylee

    abbylee New Member

    I take Methadone myself. I get 240 pills for $30.00 - $35.00 a month. I just wish that were true for my Singulair and Zyrtec.

  5. elsa

    elsa New Member

    I'm not on any antidepressants but my husband is so I'm interested in your post.

    Does the article say anything about the improvement on side effects? It was my understanding that the newer ones had less sexual side effects and less weight issues attributed to them.

    My husband takes a tiny amount of lexapro in the pm for sleep and wellbutrin in the AM for depression.

    Thanks for posting this. Take care .......

  6. BxGirl

    BxGirl New Member

    I can tell you that I took the older and the newer ones. I definitely like the newer ones better. The older ones had more side effects and made me feel funny.

  7. abbylee

    abbylee New Member

    No, there was no mention in less side effects, however, there was mention of withdrawals being worse with the newer drugs.

    I can believe that as I had awful withdrawals from Paxil and other newer drugs, but none to speak of from Trazadone and/or Elavil.

    abbylee PS - Also heard that Paxil has been linked with birth defects.

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