I feel that thread had too many different conversations going... Thanks as always for your interest in researching the cause of these poorly understood illnesses. It is very frustrating to be dealing with these illnesses when there is so little known about cause, effect and proper treatment. I also have high Rnase L and Elastase levels as well as an elevated C4a. Any thoughts on how all those play into these illnesses? I see others here with those same issues. We had our house tested for mold ( there was non found ). Dr. Vrchota suspects chronic Lyme for the C4a elevation, but she said any neurotoxin could cause the high levels. I wonder of on-going food sensitivities could be causing this type of inflammation?