I have CFS and borderline Narcolepsy although I just think it is all CFS. I am on 60 mg a day of Ritalin, broken down into 6 10mg pills (the 4 hour kind). This has been the only way for me to function halfway normal. I take one when I wake up and every two hours after that. Lasts me all day at work and I avoid the crashes in between pills. I do crash at the end of the day, but better than getting the crashes throughout the day. I have ADD as well and it helps with my concentration. The only side effects I have noticed is more dry mouth, excess sweating (which I do anyway)and my pupils are huge...I don't like the Extended release tabs as they tend to keep me up at night. If I crash too much by the time I get home I may take 1/2 a tab and then my Ambien CR overrides that when I go to sleep.