I was diagnosed with FM/CFS almost 3 years ago and have found a wonderful doctor who has helped me get a portion of my life back. I am still having a hard time with energy, nighttime pain and sleeping. This past visit my dr. gave me a B-12 shot for energy and perscribed zanaflex at bedtime. I am currently on Ultram for pain,up to 8 50mg tabs a day,and take Ambien for sleep as well. She also gave me a prescription for Klonopin if the Zanaflex is not helpful. The b-12 shot helped for about 4 days and now I am back to zilch energy, and I slept thru the whole night the first night I took the zanaflex, but now it is back to only sleeping 3-4 hours a night. Should I try the Klonopin- I also am taking ZMA as well as numerous supplements. I am so confused- Sometimes I wonder if I should get off all supple. and meds. but I don't ever want to be in as much pain as I was 3 years ago. What do I continue to take? What do I quit taking? Help! Any suggestions?