Theres a few sleep topics going at the moment and i have done abit of research over the years on it. I deally we are searching for good old stage 4 sleep, but we really dont know if we're getting it or not unless we're hooked up to a machine in a lab. So i have come to the conclusion of not worrying about this but just finding medication or combination that can give me a good long sleep of atleast 8 hrs and i wake up feeling rested. I think its a trial and error thing as well, its written that traditional benzos interrupt normal sleep patterns but i think if your getting good sleep and waking up feeling good/ok then your doing well. I find taking a combination of things works well as i think us with cfs getting sleep is especially hard to come by. Obviously run things by your doc, basic list of things for sleep, Benzo's eg valium, tamazepam, mogadon,klonopin, Z-drugs- zopiclone/imovane, zolpidem/stilnox/ambien sedating anti-depressants- mirtazipine/avanza, doxepine/deptran, endep/amitriptyline, surmontil Antihistamines- phenergan/promethazine, atarax, doxylamine/restavit Others- seroquel, lyrica, gabapentine/neurontin, topamax. What i have found is using one of the benzo's or z-drugs to help get to sleep with an antihistamine or a sedating antidepressant to help u stay asleep and give you deep sleep. I also recommended changing things up regularly so you dont build up a tolerence to a particular medication and it stops working etc and it helps keep your dosages low. Also if you find some natural things help like valerian etc you can try adding them in there somewhere. Jaminhealth has a good little combo of natural and medication she has found effective for her. I just think sleep is so important to cfs, without it we will never recover. I dont think its the whole storie but without it your going to feel 100 times worse. Im averaging a 9 out of 10 at the moment but with a few nights of poor sleep im back to a 5 or 6 pretty quick. cheers!!!