I don't grasp that article. DHEA is a hormone, I believe. My fibro doc said I had "almost no adrenal function". He put me on low dose natural cortisol - 5 mg I believe - every morning. Every night I have to take 100 mg of Pregnenolone. I thought "sulfate" was it's own substance? I was going to take the epsom salts internally (bag said only for a week) because I take magnesium anyway, so thought that way I would be getting sulfate as well, as we seem to need that. I wonder if there's another form to take it in, by capsule, that won't cause headache. I'm not one who can sit and soak my feet - I just don't have the energy to go to the trouble. The price of the Kirkman cream you recommended came down, so I might order that. I had ordered "magnesium oil" from vitacost, but I guess you need the sulfate form? I think this form is magnesium chloride. Began low-dose naltrexone last night. Got extremely ill about 1/2 hour after taking; but I think it's because the famvir & celebrex & antihistamines have ripped my stomach up. I KNOW fibromyalgia is related to gut health. As soon as I develop digestive issues, my fibromyalgia goes through the roof. I just "proved" it again last night: spasms in neck hurt so bad I couldn't sleep. Had hard time getting out of bed & had to take painkiller. I came across info while researching yesterday, that may be of benefit to you: read that Alpha Lipoic Acid helps "endothelial function". I know you were looking to improve that. If you're concerned about it, maybe you can try taking a lower dose. Pure Encaps has 100 mg. I'd feel safer sticking to Andy Cutler's protocol.