spacee – Dr. Nicolson [antioxidants and lipids] I have read where you now are using antioxidants and lipids to fight the mycos. Are there any specific brands you prefer? And any you do not think are helpful? Linda Reply: Chronic intracellular bacteria (Mycoplasma, Borrelia, Chlamydia, Ehrlichia, etc.) increase the production of Reactive Oxygen Species (ROS) inside our cells, and our mitochondria are especially susceptible to this type of oxidative damage. When mitochondrial inner membrane lipids are oxidized by ROS, they become leaky and the electrochemical potential across the inner membrane cannot be maintained, resulting in loss of electron transport and reductions in high energy molecule production (ATP, NADH) and eventually in important cellular reducing molecules like reduced glutathione, resulting in fatigue that is not eliminated by rest. In most degenerative and chronic diseases, this is a problem, including CFS and other fatiguing illnesses. We have found that replacement of the damaged membrane phosholipids in the mitochondria (I call this Lipid Replacement Therapy) restores mitochondrial function and significantly reduces fatigue. We have used unoxidized membrane phospholipids, such as NT Factor plus antioxidants, to replace damaged lipids in various membranes, including the mitochondrial membranes. This all natural ingredient NT Factor can be found in several commercial products that fight fatigue and restore mitochondrial function.