This isn't a good idea to do at the same time. I've felt so poorly the past couple days it has frightened me. I started off very slowly with the methylation protocol then went to it every 2 nights. I started feeling horribly fatigued, weak, dizzy, etc... on Saturday I'm on antibiotics for lyme, babesia herbs, colloidal silver for viral issues. I don't know what my doctor was thinking having me start another antibiotic and methylation at the same time. I don't know what has caused what at this point. I'm waiting for my doctor to get back to me. I feel a tad better today.