Search Fibromyalgia & Chronic Fatigue Syndrome Advertisement Newsletters & RSS Email to a friend Print this Page My doctor prescribes Xyrem to his patients that have Firbo. He said that he is having great success with this drug. I found the following article that I thought you might me interested in: Narcolepsy Drug May Hold Hope for Fibromyalgia Patients A lack of deep, quality sleep is one of the major problems experienced by fibromyalgia (FM) patients. It has been theorized that this lack of restorative sleep may even be the primary cause of the pain and fatigue that are also key symptoms of FM. A clinical study conducted by researchers from the University of Texas Health Science Center at San Antonio and the Oregon Health Sciences University in Portland found that the drug sodium oxybate, currently used to treat cataplexy in narcolepsy patients, was effective in both improving sleep and reducing pain perception for FM patients. Study Criteria According to a press release issued by the University, Dr. Sponsored Links Narcolepsy Treatment How Narcolepsy affects alertness. Learn more at the official website. www.AlertnessMatters.com Can't stay awake? Find it difficult to stay alert? get $5 to answer 4 surveys. www.ExcessiveSleepinessPoll.com Fibromyalgia Center Our Medical Doctors specialize in fibro. Sign up for free newsletter. www.FibroAndFatigue.com I. Jon Russell, associate professor of medicine at the University of Texas Health Science Center at San Antonio and the study’s lead researcher, along with his colleagues Drs. Robert M. Bennett in Portland and Joel E. Michalek in San Antonio, conducted a randomized, double-blind, placebo-controlled, multi-center clinical trial. The centers randomized 188 fibromyalgia syndrome patients to receive active treatment with one of two doses of sodium oxybate or with a placebo. One active treatment group took 4.5 grams of sodium oxybate per night, while a second group took 6 grams per night. The sodium oxybate was administered at night in two oral doses. The trial lasted eight weeks. Before they began to take the study medication, all of the study participants were withdrawn from other medications used to treat their fibromyalgia symptoms. Of the 147 patients who completed the trial, 51 took 4.5 grams per day, 44 took 6 grams per day and 52 took a placebo. Study Results “We saw significant clinical benefit with both doses of sodium oxybate compared with placebo,” Dr. Russell stated in the press release. “The patients’ self-reported pain and their perceptions of how well they slept improved among both dosage groups. The tenderness found during in-office examinations was significantly improved with the 6 gram dose.” Disclosure Sodium oxybate is marked in the U.S. as Xyrem and is produced by Orphan Medical, a subsidiary of Jazz Pharmaceuticals, which funded the study. Because no medication is currently FDA approved for treating fibromyalgia, physicians must treat the disorder with medications officially approved for other purposes. It is up to every physician to determine whether Xyrem, or any other medication, is appropriate for each individual patient. As with any new drug or new use for a current drug, additional studies will need to be done. But when promising results are reported for any new treatment option, it helps keep hope alive for the millions of us living with this disease.