This frightening symptom first occurred in July, 2015. I woke up and could not get out of bed! I could not get to the toilet! I was 66 at the time and had never experienced anything like this! I suffered for over a week, made 2 trips the the ER and 1 to my doctor, all by ambulance of cabulance. Finally I was prescribed prednisone. The regimen was 10 mg pills, 4/day for five days, then 2/day for 5 days, then 1/day for five days. Two hours after taking the first dose, I could stand and walk again! What a relief! I subsequently saw neurologists and rheumatologists but they found no problems. One ER doctor diagnosed arthralgia, but I doubt this is correct. Yesterday, five months after the first incident, it occurred again, but with an added symptom. I was awakened at 5:00 a.m. with agonizing (level 10) pain in my knees plus the inability to stand or walk. I had a prescription of prednisone on hand and my doctor told me to begin the same regimen. Again, 2 hours after taking the first dose the pain had receded and I could stand again. I am now on my second day of prednisone. After I complete this regimen, I intend to keep a supply of the medication on hand in anticipation of another recurrence. I know prednisone is a cortical steroid and is not intended for continuous usage, but only to be used when the symptoms present. No one can tell me what is the cause of this frightening symptom. Naturally, I am very concerned. I am now 67 and if I lose the ability to stand and walk it is going to be disastrous! I don't know where to turn for help. I keep searching online but with no success. If you can help point me in the right direction, please respond. Thanx!