I'm being treated through the FFC. I have been on 10 mcg of T3 for less than a week. Already, my hands are not cold anymore! Then I stepped on the scale today, and I realized I had lost five pounds. I do have to keep up the cortisol as well for adrenal exhaustion, but I am having no problems with either of these meds. It's so surprising what just a *little* of this stuff will do!