Tansy,..a question on 5HTP,..please

Discussion in 'Fibromyalgia Main Forum' started by tandy, Aug 10, 2005.

  1. tandy

    tandy New Member

    Hi Tansy~
    I searched briefly on the supplement 5htp.
    Sounds like something I wanna try,for both sleep,energy and mood.
    your pretty informed in all this nutritional stuff and thought I'd ask if your aware of any BAD things about this supplement?

    Also,... Me having endometriosis,... just wanna make sure there are no contradictions on taking them.
    (meaning,..they don't in anyway effects hormones do they??)

    Might be a stupid question, but it never hurts me to ask.
    No shame in my game! lol
    Thanks for your help
    Tandy :)
  2. tansy

    tansy New Member

    5 htp should not be a problem, in fact it is often recommended in alternative protocols for endometriosis.

    Whenever we take anything like this there can be a knock on effect, good or bad, on us globally. What is often referred to as hexing can occur if a supplement or alternative makes the IS system more able to kill of the pathogens many of us have. The same goes for anything used to detox.

    IMHO we should aways start anything new on the lowest possible dose then increase it slowly until we find the optimum dose. This not only lessens any adverse effects if we try something that's wrong for us, but it gives our systems a chance to adapt to any physiological changes, which is an important consideration in these DDs.

    love, Tansy
    [This Message was Edited on 08/10/2005]
  3. tandy

    tandy New Member

    I knew you'd at least know if it were a good supplement to try. And would let me know as to any bad side effects.
    I'll start at 50 mgs a day unless a smaller dose is needed,...depending on the herx(if any).
    Some take more a day but thats a decent start anyways.

    Huh? good to know that 5htp is mentioned in some alternative therapys for Endo. I was'nt aware of that.
    I may try to google search that.(5htp for Endo)??

    Take good care,..and Thank you loads!!
    Tandy :)
  4. tansy

    tansy New Member

    is becoming more available now and some who have used both say tryptophan works better. Might be worth checking it out as well.

    love, Tansy

  5. tandy

    tandy New Member

    ??? I can't recall where??
    I'll search that one too.
    Your right,..I might be better off.

    I have catalogs from both Swanson and Puritans.
    I'll look in there also. Just to see what is listed as "use for" for trytophan.
    Is that an amino??
    Thanks for mentioning :)
  6. tansy

    tansy New Member

    Eat Turkey, Be Happy
    Chemical in bird may affect mood and memory, study suggests
    By Serena Gordon
    HealthScoutNews Reporter

    THURSDAY, Nov. 28 (HealthScoutNews) -- It may not be the company of family and friends that's making you feel good this Thanksgiving Day -- it could be the turkey.

    A chemical in turkey called tryptophan has received a lot of attention for its ability to make you feel sleepy, but Dutch researchers say tryptophan may also affect your mood and memory.

    In a study in the current issue of Brain, Behavior and Immunity the researchers, from the University of Maastricht in The Netherlands, found that tryptophan depletion altered people's moods and cognitive function, particularly in those with a family history of depression.

    Tryptophan is an amino acid, and a precursor to the brain'schemical messenger, serotonin, which is known to play a role in depression. Tryptophan is present in many foods, including turkey, milk, bread, cheese, and bananas. But many of the foods high in tryptophan can actually deplete the levels of this chemical in your body because they are so high in other amino acids that cancel out the effects of tryptophan, says Wim Riedel, lead author of the study and an associate professor at the University of Maastricht. When you eat foods high in carbohydrates, tissues in the body are able to pull amino acids from the blood. However, tryptophan is not absorbed this way and stays in the bloodstream, where it becomes available to the brain.

    But during digestion tryptophan competes with other amino acids to cross the blood-brain barrier. If there are many other amino acids present, tryptophan gets crowded out, according to Joy Short, assistant professor of nutrition and dietetics at Saint Louis University in St. Louis. Short was not involved in the current research.

    For the current study, the scientists lowered tryptophan levels in 27 volunteers, 16 of whom had a family history of depression, by having them ingest a drink full of these competing amino acids.

    Tryptophan depletion reached its peak six hours after the volunteers drank the amino acid mixture. The researchers noticed behavioral changes in the subjects at this time: half of the volunteers with a family history of depression reported feeling blue, while 9 percent of those with no family history of depression noticed a change in their mood. These changes didn't last, however. Tryptophan levels and the volunteer's moods were back to normal by the next day.

    The researchers also found that memory was affected during tryptophan depletion. The study participants had trouble recalling and recognizing words that they learned during the tryptophan depletion, but had no trouble recalling words they had learned when their tryptophan levels were normal. Interestingly, recall of old memories, verbal fluency, and listening ability were all improved during the tryptophan depletion period.

    The authors suggest that these findings may have implications for people who have a family history of depression, and therefore might be more vulnerable to fluctuations of tryptophan levels. The findings may also affect people who diet frequently and those undergoing immunotherapy for cancer because these can affect tryptophan levels.

    "It has been shown in other research that protein-rich, carbohydrate-poor meals lead to relatively lower tryptophan levels whereas meals with the opposite composition slightly increase tryptophan levels," says Riedel. "Apart from that, dieting lowers tryptophan as well as certain metabolic diseases such as irritable bowel syndrome. Interferon treatment for cancer also lowers tryptophan and, finally, chronically elevated levels of cortisol may lower tryptophan levels."

    Does that mean we should all eat carbohydrate-rich diets if we want to be happy? No, says Short. "Tryptophan is not a magic bullet for treatingdepression," says Short. "The effects of administering tryptophan through diet are small when compared to the drugs available to treat depression," she explains.

    But, she says, this study provides another piece of the puzzle on the food-mood connection, and may give depression researchers a reason to possibly try developing therapies with tryptophan.

    What To Do

    For more information on tryptophan and mood, visit the Nutrition for Optimal Health Association . For an explanation of how tryptophan can make you sleepy, check out HowStuffWorks web site.

    SOURCES: Joy Short, M.D., R.D., assistant professor of nutrition and dietetics, Saint Louis University, St. Louis; Wim Riedel, Ph.D., associate professor, University of Maastricht, The Netherlands; November 2002 Brain, Behavior and Immunity

    [This Message was Edited on 08/10/2005]
  7. elsa

    elsa New Member

    Just a quick add on. Be sure you're not taking any SSRI's or any other rx medication that influences serotonin levels. 5-HTP works just as well, if not better then these prescription anti-depressants and combining them together could be very bad for you.

    Just thought I'd through that out there...LOL

  8. tansy

    tansy New Member

    and a very important one too.

    love, Tansy
  9. tandy

    tandy New Member

    and Thanks again~
    I did know that Elsa. I had read that before.
    I don't take any anti-depressants currently.
    I stopped 2 yrs ago when after trying a few different ones,...I felt no better on them.
    Although my dr. did'nt like the idea,..(of course!) I wanted off, and did just that.
    I do take on occasion a melatonin to aid my sleep.
    I could give that up if I need too.(???)
    Just to see how this other works,..hopefully it'll be better than.
    I wonder if theres such a thing as too high a level of Serotonin??
    (here I go with more questions!lol)
    sorry :)
    Thanks to you both
  10. elsa

    elsa New Member

    I think you'll like 5-htp then. It is one of the best acting supplements available. If it didn't interfer with my particular sleep disorder....( 5-htp suppresses REM sleep ), I'd still be taking it. 5-HTP was fabulous for my FM headaches.

    Good luch with it....


    P.S. Just for the record....I want a gold star for keeping a thread straight that only has Tansy and Tandy conversing. I did REAL GOOD seperating which "T" was saying what!!! LOL[This Message was Edited on 08/10/2005]
  11. tandy

    tandy New Member

    Good point hunny!! you DID do a good job!!

    It sure is kinda confusing huh??
    3 yrs ago when I chose that user name I noticed the next day a tansy. Well my first thought was "sheeesh,..copy catter!: lol
    but she was here long before I was~
    so I guess that makes ME that copy catter.

    You did great! better then I would've/could've.

    I may get out and try to find one or the other today~
    Thanks for your help/input!

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