This is an article by Dr. Mercola: http://articles.mercola.com/sites/articles/archive/2010/10/29/high-dose-iv-vitamin-c-found-useful-for-near-terminal-swine-flu.aspx All of us know that there is a infection factor in CFS/FM. I've had Vitamin C IV, they killed off a lot of infections. It didn't cure me, but...I sure as heck feel better. The GI tract only absorbs ~65mg of C, its water soluable so we pee it out quick. Hence, Dr Myers logic for an IV type. The best compromise of this would be to fill an old soda bottle with 3 grams of vitamin C and water or juice and consume slowly over the day. Too much C will give you diarrhea, how much is too much? Each person is different.