the downside is to find someone who will subscribe it-the doctor I see now is a a psychiatrist who is head of the pain managemnent clinic at a hospital. SHe is a big bitch and I cant stand her but she is the only doctor is KC that will subscribe what I am taking. No other doctor would touch me after my rheumy had to get rid of his patients taking narcotics ! anyway my last resort was the methadone clinic and they referred me to who I see now0-I take alot of stuf but if finally works and it lasts longer than the other stuff I was on. I take morphine 3x a day, 6-8 percocet prozac, wellbutrin amitrptyln, xanex, celebrex and skelaxin which is a muscle relaxer. Its alot of shit but I am recovering alcoholic so I figure I have an off the wall tolerance for drugs. I think the morphine and the percocet help the most but there are days I take everything and I am still in pain. I guess shrinks arent afraid to prescribe this stuff as opposed to my other doctors who wouldnt touch me. it works for me-but talk with your doctors and see what combinations work for you. good luck everyone.