Just wanted to share a statement i read in the CFS Research Review i got in the mail. "Dr. Meirleir also stated that activated OAS can suppress the thyroid even though thyroid function tests appear normal." HmMMMMMMMMMM..... i have cfs and makes me wonder cause i have anxiety...constantly hot..etc. It also states OAS effects RNaseL which can cause symptoms including hypersensitivity, depression, increased pain, and hypoglycemia and vision symptoms. Maybe they are on to something with this.