I have been taking t3/t4 combo for about 3 years. About 9 months ago it was raised to 3 grains. I have been having increasing joint pain especially in my knees. I never made the connection. All of my other symptoms seem my thyroid would be low but the labs say it is fine. So I stopped taking anything for almost a week now and nothing! All the joint pain is gone! Has anyone else had this. I don't want to go back to the Holtorf.