All this time I thought I was crazy HA!! I am new to this forum today and I must say it is the most wonderful, informative site I have encountered to date. No, really. I have suffered from PTSD anxiety and depression for a long time and found out in the last 2 years I also have Osteoarthritis and Osteoporosis, to the extent I fractured my back in a 6 inch fall. Coming with this is the revelation by many doctors I am either just making up the pain (it should be gone by now). But, a visit to a rhuemetologist yesterday and lots of tests confirm I do have real pain and suffer and have for a long, long time FM and CMS as well as the OP and OA and maybe RA. He prescribed prednisone and deseril for now till the rest of the tests come back. The first 5 hr unbroken sleep I have had in many years. He also tells me it it the same as the Methedone that is in Darvocet that has afforded minimal relief at best. But the sleep was great. Does anyone know if it builds up in your system and offers greater relief over time?