It seems that many e-mails in response to gcalex post, including my own, didn't "take" so I'm starting a new chain on the subject. I have not found any supplement that has worked for me. I spend thousands of dollars a year on supplements: vitamins, minerals, herbs, enzymes, probiotics, homeopathic remedies, essential fatty acids (borage, evening primrose, EPAs), Co-Q 10, Enada, etc. yet nothing has helped my CFS or FM symptoms to any degree. I always take the supplements for long enough periods of time, and at high enough doses, to give them a fair trial. Despite my lack of success in finding any helpful supplement(s) for FM and CFS, I expect to keep on trying more supplements in the hope that something will help. Hope springs eternal! And I expect to continue taking vitamins, minerals, herbs, enzymes, essential fatty acids, etc. in the hope that they are helping me on some level that I can’t feel.