Hello, I just started using the Duragesic patch and it has been working really well (50mcg). I had a problem with them sticking etc so I heard/read to get med tape for them......did that, and they still would come off etc - pain in the butt, but I kept trying because I couldn't believe I could actually "simply" go to the park and swing my toddler son up over my shoulders, go shopping and lift certain things. Anyway, I read I needed to get to brand vs the generic as far as them sticking better and they work better - so I did. I got the brand, which was expensive, but I din't care; I did at first, but there we all go "when you are in pain, you JUST want to be able to have a life and give it a go!!" I get them, and followed the directions to the "T" and then one fell off within hours and I lost it; couldn't find it - worring my baby woould find it too. I had to put a new one on. I also noticed, that I don't think the brand works as NEARLY as good for pain relief as the generic. I have to take more breakthrough medication because I am not getting the releif I did with the generic. I just have some questions for you for some help to encourage me on what to do with them! For the first time (when on the generic), I was able to wake up, not have to wait for my meds to kick in to help my children, or eat.....just simple things everyday people can do and I am really excited to continue the patch but need to fine-tune how they work. I would appreciate ANY feedback on my questions below as to what helps you - I know we are all different, but I need some encouragement. If these patches don't end up working, I am literally ready to give up on all meds/herbs and just live with the pain. I have children to take care of and I am sensitive to medications (a lot of fibro patients are) and I can't hang some with freaky side affects, but these patches haven't given any weird side affects - thank God, so I am being very optomistic/patient about the patches. Thank you SO much for your time! (1) Have you tried the generic and the brand and if so, did you notice a difference in the pain relief and the the way they stick? (2) What type of breakthrough medication(s) works for you and appox how often do you think you have to take it a day? (I know everyday is different depending on your activity level, but approx). (3) How long have you been on them? (4) Where is the best place to apply them that works for you? (I have been rotating my upper arms) (5) How long where you in a certain MG(or mcg) before you had to go higher? I hope you all are having a nice weekend and getting a chance to get some rest! Have a good day.