For what it's worth, the researcher Dr. Montoya at Stanford had tremendous success in a preliminary trial with bedridden patients using the AV drug Valcyte. According to his report, the majority of them were up and about (some even working) within a short period of time. This is by no means a conclusive study, of ccourse. Whether you want to try is dependent on your tolerance for risk. And from what I've been hearing, starting with a very tiny dose of AV's and then gauging reactions is far better than starting too ambitiously. (If a small dose does give you a herx, you always can back off.....AV herxes seem to go away reasonably fast, especially if your liver is in good shape.) This certainly is not advice. Just a comment that maybe considering them seriously is worthwhile regardless of what state you're currently in. BTW, which AV is the FFC recommending for you? Keep us informed please. I am trying to keep tabs on everyone who's experimenting with AV's, since so little is known about them with regard to CFS patients and sharing info seems to be really helpful. Thanks!