Has anyone had an adverse reaction to trazadone?? I took 25mg for the first time last night and could not sleep. Altho I was alittle groggy I felt wired. Coud be I've been taking Ambien for so long I was have having trouble sleeping without it. Most people seem to sleep welll with Trazadone. I'm exhausted today from no sleep. Thanks! Janana.PS Im very sensitive to most meds. What knocks most people out speeds me up!!