Hi all, I have had fibro for years. It has been under control for the most part taking trazodone at night and an ssri during the day. I have had flareups, but then they went back down. I have been lucky. My problem is this. I have been taking trazodone for 28 years. It has helped with pain and sleep, however for the last year, the trazodone itself causes some pain for the first two hours. I know this, because each night I don't have the bad pain UNTIL I take my dose (50-75 mg). I have to rough it out, lose sleep, THEN it helps with the normal fibro pain. This is very discouraging, because when I try to wean off of it due to this problem (to try something else) I get such bad pain I can't tolerate it, and I lose sleep. I was wondering if anybody else has noticed increased pain from the trazodone. I did look it up and one of the less common side effects is muscle pain, but I didn't have this for all these years! I can honestly say that the trazodone has helped with pain and sleep, it's just this initial pain about 20 minutes after I take it that's hard to bear. I literally cannot sleep until this pain subsides down to "normal" pain.