About 6 weeks ago, I changed to sertraline for anxiety and resulting depression. First two weeks were really good. Then, the last couple of weeks my anxiety seems to have increased. I also take 1/2 tramadol in the a.m. and 1/2 .5 xanax in the afternoon if needed along with anothe 1/2 tramadol if needed. Lately, I have had a lot of tension headaches, probably from sitting at my desk too long, so I have added advil if needed. Something seems to not be working together very well. I get jittery feelings in my stomach as soon as I wake up and feel like I need more xanax, so will take 1/2. Still not right, so I take 1/2 tramadol, and then I seem to calm down. The last few nights, I have gotten these same jitters after I take my night time meds which are: 50mg. trazodone; 25mg. atenolol; .5 xanax; and pericolace and/or dulcolax for chronic constipation. Also, try to take metamucil morning and night. This jittery feeling in my stomach is keeping me from being productive at work. All I want to do is sit and stare, or lie down and be still. Anyone have any thoughts on what is going on? Any input will be greatly appreciated!