Hi, I am a male who has arthritis and FM. I have been taking ULTRAM 50mg/8 per day (2 at a time) for about 5 years. Although it is not a narcotic, you will not be able to get by without it. It definitely makes a difference in the level of pain, especially if combined with an anti depressent ( I have been on all of them). It really will make your mouth dry, other than that, no side effects, can be taken on empty stomach.