What happen to it? I've said before that what is upsetting to me is the number of people that I know of that have gotten improvement and then just cut the MB and the rest of us still dealing with this DD out of their lives. If I'm blessed enough to have that happen rest assured that I'll let you know. I did Valcyte from August 07 to February 08 with Dr. Montoya. And yes it was a very hard ride BUT I did get cognitive improvement. I can balance out my check book and I even transfered money from my IRA without my husband having to walk me through it. I would not have been able to do either before Valcyte. However my energy is still very low. At my April appointment with Dr. M. (I cannot always get an appointment when I want it as he's a pretty busy fellow) he put me on Valtrex 500mg. I saw him again in June when he referred by to the Pacific Fatique Lab program (they only take people that are refered by 4 of the CFS specialist) I am currently following a program outlined with them. I saw Dr. M. again last Wed. The good news is that all of my viral titers are now low. I forgot to ask for a copy of my lab work but he did seem very happy that my HHV6 which was over 1500 in 07 is now 30. Sounds great but I still have no energy altho in the last 4 months I've only had one day that was so bad I had to go back to bed and that I really appreciated. I don't do much other than read (oh yes I can read and remember what I read) and watch T.V. Due to the program set up at PFL I now use a power chair, shower chair, stair chair so Im not wearing myself out just standing and walking. I had struggled with the possibility that he would want me to go back on Valcye and I had made up my mind that I would but in view of the low HHV6, CMV, HS1 and I forgot to ask about the EBV also being low but what he did was triple my dose of Valtrex a drug I've had no side effects from. Doctor said he has seen people with good improvement overall, people with cognitive improvement and the energy finally comming along much more slowly. So he thinks there is still hope for me as do I. Either way I am so happy about what I can now do that I haven't been able to do for so long.