Visible and near-infrared spectral changes in the thumb

Discussion in 'Fibromyalgia Main Forum' started by Bluebottle, Mar 3, 2009.

  1. Bluebottle

    Bluebottle New Member

    not quite sure what it means, but it's more proof that we have a physical illness:

    "Visible and near-infrared spectral changes in the thumb of patients
    with chronic fatigue syndrome.

    Journal: Clin Chim Acta. 2009 Feb 24. [Epub ahead of print]

    Authors: Sakudo A, Kato YH, Tajima S, Kuratsune H, Ikuta K.

    Affiliation: Department of Virology, Center for Infectious Disease
    Control, Research Institute for Microbial Diseases, Osaka University,
    Yamadaoka, Suita, Osaka 565-0871, Japan.

    NLM Citation: PMID: 19248775

    BACKGROUND: Chronic fatigue syndrome (CFS) patients show a persistent
    fatigue condition with muscle pain and impairment of concentration,
    memory, and sleep. Presently, the physiological basis of CFS remains
    unclear. In this study, spectroscopic differences in the thumb were
    compared between 103 CFS patients and 122 healthy controls to examine
    possible changes of levels of oxygenated or deoxygenated hemoglobin.

    METHODS: Visible and near-infrared (Vis-NIR) spectroscopy was used to
    examine possible changes in the region of 600-1100 nm.

    RESULTS: Vis-NIR spectra showed sharp peaks at 694, 970 and 1060 nm
    and broad peaks in the regions of 740-760 and 830-850 nm. As these
    peaks are possibly related to oxyhemoglobin, cytochrome c oxidase and
    water, levels of these factors were compared between the two groups.
    Statistical analysis of the absorbance of Vis-NIR spectra showed a
    significant decrease in water content, a significant increase in
    oxyhemoglobin content, and a significant increase in the oxidation of
    heme a+a(3) and copper in cytochrome c oxidase in CFS patients.

    CONCLUSIONS: These changes imply accelerated blood flow and energy
    metabolism in the thumbs of CFS patients."