I am taking 150 mg of Lyrica twice a day and all was fine except for the fatigue part. Today the Lyrica decided to stop working and I get waves of pain all up and down my body. My digestive system is screaming at me now too. I guess I need to just vent because I don't know what else to do. I have a doctor's appointment on Monday but tomorrow is going to be a long day. I have been so tired this past week that I can't even do much at the computer. I took something to help me sleep and maybe that's what I am going to do. When things work they work well when they stop working it's hell.