Why Do Benzo's Help With CFS?

Discussion in 'Fibromyalgia Main Forum' started by greatgran, Feb 15, 2009.

  1. greatgran

    greatgran Member

    I do know that xanax help my cfs symptoms and the anxiety/depression but not sure why. Any input on this.

    Thanks and God Bless,
  2. sleepyinlalaland

    sleepyinlalaland New Member

    a reply to kjm's post (titled slippery slope) about the reason why benzodiazapams (sp?) are so helpful for sleep. Because in the article they describe chronic insomniacs from suffering chronic hyperstimulation of the nervous system, it may relate to why benzos are so helpful for you. Below is a little bit of the article that was published in the medical journal SLEEP last November. (note they are referring to a GENETIC discovery found in folks with chronic insomnia...which I assume most fm/cfser's also have)


    GABA is reduced in the brain of individuals with insomnia, suggesting overactivity is present not only at the level of excessive thoughts and emotions, but can also be detected at the level of the nervous system," said principal investigator Dr. John Winkelman of Brigham and Women's Hospital, which is a teaching affiliate of Harvard Medical School in Boston, Mass.
    The study also reports that many of the hypnotic medications that are most effective in treating insomnia are benzodiazepine receptor antagonists
  3. ladybugmandy

    ladybugmandy Member

    i have had this experience as well. i think the benzos keep neurons from firing as quickly or something......cheney has an article on that.
  4. Mikie

    Mikie Moderator

    Believes that we are in a constant state of slight seizure activity in our brains. That means that we cannot move into the slight coma state which is sleep. He prescribes Klonopin to help with the misfiring and overfiring of the brain's neurons. He even believes that the Klonopin protects the neurons from premature death. Studies seem to support that Klonopin interferes with the transmission of pain messages in the brain. Thus, it would appear to help with both pain and sleep issues.

    Twice, I have tried to wean off the Klonopin but was unable to. Dr. Cheney believes that when one recovers sufficiently, it is easier to wean off. The first time I tried, I found myself very aggitated and jumpy. The second time, I just got fatigued as my sleep quality deteriorated. I also noticed pain was coming back. I had assumed that it was the Guai alone which had relieved my FMS pain but my specialist says it's a combination of the Guai and the Klonopin.

    I will try to wean off again down the road when I believe my healing is at a level where I can try again. I have accepted that I may have to take it the rest of my life. I continue to heal but progress is slow. I have to look back to see where I was and where I am now. Sometimes, it's tiny improvements which signal to me that I'm still recovering.

    Love, Mikie
  5. Achyten

    Achyten New Member

    I've been on klonopin for at least 25 yrs,,, and it helps me so much yet. I was always on 0.5 mgs,,once a day,, and the last year I"ve had to up it to another pill,, same dose,but at night. It does help with the sleep,, and spasms I have in my legs. I know its a long time to be on it,, but if it still helps me after so many years,, I don't care.
    So, I"ll be on it for the rest of my life. Though I have worried about what it might be doing to my kidneys, etc.,,,I have to some quality of life,, while I am here.
    I"ve tried so many pill killers,,,, and nothing works for me except oxycontin,,,so I also take that as well,,,not to mention being hypothyoidism,, I have to take synthroid,,also take trazadone for sleep as well. I just started taking a bp pill too. Other than that, thats about all I take for fibro,, and its enough. I hate having to be on pills. I guess we're all like that,,,no doubt.
    And,, now I"ve been so sick with my gall bladder issues. Been in the hospital twice these 2 weeks.
    Had an ultra sound done and it shows I have a swollen gall bladder,, or a distended one. You'd think that'd be enough to have my gb out,,,,,,,,but no, I have to go another test on March 2,,, too far away for me,,with suffering so much. Then, hopefully they'll take the darn thing out. I"ve been sufffering from this for years,, and no one does a thing for me,, even though I"ve had to go ER several times. I just don't get it.
    Oh well, enough of my complaining,,, lol.
    Has anyone ever had to go through the gall bladder thing like me? I"d sure appreciate some feedback on this,,please?
    Hope to hear from someone!!
    Please take care,,,
    Love & Gentle Hugss, Achyten
  6. TaniaF

    TaniaF Member

    I'm sorry you are going through this--I did too! After pleading with my Gastro to order the final test (nuclear biliary scan, sometimes called HIDA scan) I was diagnosed with Gallbladder dyskenesia. My gallbladder had no stones; it just wasn't working. You will get a ejection percent after the scan. A normal GB should be 30% and up--mine was down at 9%.

    Two weeks later I had my GB out via laproscopic surgery. It was one night in the hospital, minimal pain (I only used Tylenol when I got home) and the yucky, achy feeling went away. I did have some (what I call) "brain fog" after the general anesthesia. I tried to warn the doctor that I had either fibro or CFS.

    Now, my only advice is to maintain a strict low-fat diet. If you dive into fatty foods you can get sick and have diarreah.

    Good luck to you!

  7. Achyten

    Achyten New Member

    I was so happy to see your response... especially with you having experienced the same thing I"m going through. It's so reassuring to hear there will be help for me yet.
    I wondered what a distended gb was and why..
    You have helped me more than you know.
    To think if I get the GB out I won't have anymore attacks,, is such a joy to look forward to, after all these years of suffering,, and not one dr. doing a thing for a me. It seems when you have fibro,, they all slough you aside,,, thinking its all in our heads,, or we're like that cause of fibro, and refuse to look into it deeper.
    Thankyou so much, Tania!!! I apreciate so much your helping to understand what I"m going through.

    Hugssss, Jennie