Xanax and serotonin?

Discussion in 'Fibromyalgia Main Forum' started by an1000, Oct 22, 2009.

  1. an1000

    an1000 New Member

    Wanted to start a spin-off thread based on our previous thread about neurotransmitter levels...

    Let's assume you can prove from a combination of a lab, and symptoms, that you do have very low serotonin, and that your serotonin is not brought up to a therapeutic level by SSRI treatment. What role, if any, does Xanax, or other benzos, play in affecting serotonin levels? Would increased use raise, lower, or have no effect on serotonin?
  2. AuntTammie

    AuntTammie New Member

    "Severe depression may result from biochemical changes in the brain induced by benzodiazepines. Benzodiazepines are known to decrease the activity of serotonin and norepinephrine (noradrenaline), neurotransmitters believed to be closely involved in depression. Antidepressant drugs including the selective serotonin reuptake inhibitors (SSRIs such as Prozac) are thought to act by increasing the activity of such neurotransmitters."