This will be my last post detailing my adventures with Xyrem. I was fortunate to be able to try it. Unfortunately, my insurance would not cover it, so it was all out of pocket for me. I wanted to give it a fair trial, and I think it did. I have the means to continue, so I was trying to make up my mind if I should. The decision has been made -- but by my stomach, not my brain (although my brain was quick to agree!). About four nights ago, I took my usual 9/8.5 mL doses. About an hour after the second dose, I woke up in a cold sweat and feeling just awful. I'd been having brief wakenings for the past week in the early morning, and I could tell that my dose wasn't keeping me under adequately anymore. Well, this is a medicine that you really *don't* want to be awake for as it works. I spent a very uncomfortable 20 minutes in the bathroom -- never getting completely sick. My head was swimming, as you can imagine. I went out to lie on the couch for a bit, then had another huge wave of nausea, another uncomfortable 20 minutes, then I crawled back in bed, freezing cold and shaking, and fell asleep. I was 'out of it' most of the next day. I've come to the conclusion that the dose my body requires to remain under and get the therapautic effects is entirely too close to the dose that turns my stomach inside-out. Unfortunately, this has happened with other meds as well -- it's always something! So I cancelled my refill that I'd just called in. I will really miss how awake I've been during the couple of months that I was on Xyrem. That has been an absolutely godsend. I'm not sure what I'm going to do for sleep now, but I'm making headway in other areas, so perhaps overall I've moved forward, even if Xyrem wasn't a long-term solution for me.