Zoloft has been a miracle drug for me. I have panic/anxiety disorder and depression and Zoloft saved me life. I started taking it in 2000, so I've been on it for a while. However, I'm now taking the max dosage and when the effect isn't as strong, I'm going to have to get on a different antidepressent and I'm scared of that. I know that there are even better ones out there these days. I'm just afraid to try something new.