All of the information written in the article by Connie Strasheim sounds like me. Every bit of it is what I go thru everyday. My skin is very tight and darkening from taking the minocycline which does not seem to be helping after taking it for a year now. I still feel like I did a year ago if not worse. I woke up about 4 years ago and my dog had a big red spot on her back. I had big red welts on the side of my face. Put alcohol on both of us and went on. Today I'm reading articles on scleroderma, lupus and chronic fatigue syndrome and I'm experiencing some of all these. decided not to take Cellcept, Prednisone, plaquenil. I am going to be tested for Lyme next week.