It's possible to have myofacial syndrome in which the facia, the material which holds us together, gets inflamed and knots up. It's kinda like when you pull a piece of yarn on a sweater and the sweater will pile up or knot up where the yarn is pulled. A good medical physical therapist can reduce the myofacial knots and help get rid of inflammation in the area. If the knots are facia, pressure on the knot, in the sorest area, held for a few minutes, while taking deep breaths, will often reduce the pain and the know will disappear. Myofacial pain release also releases toxins so it's good to drink a lot of water afterward.
My physical therapist used a suction cup to run up and down my thigh to release the myofacial pain when he worked on my sciatica. They don't sell these little suction cups but I found a child's ball in Target which works as well. It's about the size of a tennis ball but has little spikes all over it. It's softish plastic. I rolled it up and down my thigh and it did as well as the suction cup. This can be very, very painful at first but it does work for myofacial pain. Most of us probably have this condition along with our CFIDS/ME and/or FMS.