Hi, Jaminhealth. In June I had PRP prolo done on my right knee. My left knee wasn't bothering me much then, so I didn't get it treated.
The one session helped some with the pain, but I mainly noticed that my kneecap no longer moved around when I bend down. The stabilization is a good sign. So yes, I'd say that more than 1 session is required to get significant relief.
Since then my left knee has gotten really bad and moves around when I bend all the way down. So 3 days ago I had both knees treated with PRP prolo.
I'll do another round, but not for 2 or 3 months. My doctor said there is no problem with spacing the visits like that. You won't lose benefits you've gained if you wait awhile.
I've also had 3 PRP prolo treatments done in my back and neck on one side, and it's helped a lot with pain. It's not all gone by any means, but I've drastically cut down on how much I see the chiropractor now or need to use the ball to work out muscle spasms.
Something to consider with PRP is that it can produce a MUCH stronger pain reaction than regular prolo. I find it so much more painful afterward; and, of course, the things that would really help pain like ice and anti-inflammatories are off limits since that would defeat the purpose of the treatments.
I've had an even stronger pain response to the knee PRP prolo sessions than the neck and back. It's been just agonizing and really disrupted my sleep for several days.
After 3 days, I still can't use the stairs without a lot of pain, and I can't bend down to clean the litterbox at all. Luckily, my husband has taken that over for the time being. I don't miss that chore!
My doctor said it's normal to have a much higher pain response to the PRP. Also, compared to regular prolo, you can get the same results in about 1/2 the time with the PRP as opposed to regular prolo.
So it's roughly a wash with the money in the long run. I'm willing to go through more pain and expense to get faster results.
Hope that helps,
J.